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Vehicle controls in matched PBS-BSA buffer, selective GLP-1R antagonist exendin(9-39) confirming GLP-1R-specific contributions, selective GIPR antagonist confirming GIPR-specific contributions, Semaglutide at equivalent molar concentration as the GLP-1R monoagonism reference, native GLP-1 with DPP-IV inhibitor as the endogenous GLP-1R reference, and native GIP as the endogenous GIPR reference

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Popular GLP-1 Medications The GLP-1 landscape includes several widely prescribed options: Semaglutide (Ozempic, Wegovy): For type 2 diabetes and weight management Tirzepatide (Mounjaro): A dual GIP/GLP-1 receptor agonist with significant weight loss effects Liraglutide (Saxenda): Approved specifically for weight management Dulaglutide (Trulicity): Primarily used for type 2 diabetes management Each medication has a unique dosing schedule and side effect profile that your healthcare provider can discuss during personalized consultations

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