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This double-blind, randomized, 26-week superiority trial compared 2 mg of exenatide injection once weekly plus oral placebo (n = 160), 100 mg of oral sitagliptin plus once-weekly injected placebo (n = 166), and 45 mg of oral pioglitazone once-daily plus once-weekly injected placebo (n = 165)

Dry and pruritic skin is a common clinical manifestation of SS, with vasculitis being the second most common cutaneous manifestation, and histological examination usually confirms the diagnosis of leukocytoclastic vasculitis (LCV) [284]

doi: 10.1016/j.drudis.2021.04.025 [DOI] [PubMed] [Google Scholar] 188

Systematic searches were conducted in PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov from database inception through 31 May 2025