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However, this is not the only reason

Within just an hour of taking it on an empty stomach, studies show up to ~30% less hunger, ~40% fewer cravings and ~18% lower calorie intake

Cold conditions decrease it

If your primary goal is reversing prediabetes and you can sustain aggressive diet and exercise, metformin may be a reasonable starting point

The SURMOUNT-1 trial demonstrated that participants on 15 mg tirzepatide lost an average of 20.9% of their body weight over 72 weeks
