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Originally developed to treat type 2 diabetes, semaglutide works by mimicking a hormone called GLP-1 that targets areas of the brain involved in regulating appetite and food intake
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Primary outcomes, assessed at Week 0 and Week 16, included changes in anthropometric measures related to obesity, while the secondary outcomes included alterations in reproductive hormone levels, glucose and lipid metabolism, and C-reactive protein (CRP) levels, Between Weeks 16 and 40, all participants received metformin monotherapy (1000 mg BID) to evaluate pregnancy outcomes
