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Roell, J.S

B12 supplementation with tirzepatide or semaglutide with B12 addresses nutrient depletion that can occur with reduced food intake and GI symptoms

For more on the science behind these pathways, see our guide: How Does Retatrutide Work

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In contrast, in primate and human thyroids, GLP-1R has either not been detected (74) or only found in small fractions of healthy C cells (75), and treatment with liraglutide does not stimulate calcitonin secretion (76)