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However, in some cases, increments of up to 40% are required to achieve therapeutic goals [6]

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We demonstrate how human albumin fusions should be tailored to ensure a long plasma half-life and enhanced efficacy of fused biologics, despite potential C-terminal cleavage in vivo

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These trials are critical because they provide the final data needed for regulatory review. MNT spoke with Jeffrey Kraft, MD, chief of general surgery, specializing in bariatric surgery, for Palisades Medical Center in New Jersey, about this study, who commented that his initial reaction to the results was one of measured optimism