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GLP-1 (glucagon-like peptide-1) injections are a type of medication that helps manage weight by mimicking a hormone naturally produced in the body

Eligibility for the Medicare GLP-1 Bridge will also be limited to Medicare beneficiaries who have not filled a prescription under their Part D plan for a GLP-1 in 2026, and who do not have a diagnosis with a condition that is a medically accepted indication for a GLP-1 drug that could be covered under Part D (specified by CMS as type 2 diabetes, obstructive sleep apnea (OSA), and noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH)), even if they otherwise meet the clinical criteria

given its mechanism of action, this outcome was largely expected

Phentermine, one of the earliest FDA-approved weight loss medications, functions by suppressing appetite

These mimetics, featuring two noncontiguous side chains, can adopt the conformation of three different helix types and both parallel and antiparallel -sheets