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Description
Unlike pure dietary measures, weight loss may be sustained for up to a period of 3 years in the presence of GLP-1 agonist therapy [67, 68]
Due to rapid breakdown by dipeptidyl peptidase 4 (DPP-4) and renal clearance, the half-life of circulating GLP-1 is only 12 min
Semaglutide added to basal insulin in type 2 diabetes (SUSTAIN 5): a randomized, controlled trial
Providers who push faster titration may get patients to therapeutic doses sooner, but they also lose more patients to intolerable side effects
The mechanism of action involves several complementary pathways
