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The FDA label warns Qsymia may cause mood and sleep disorders, cognitive impairment and increased heart rate

Validated tools such as the Binge Eating Scale (BES) and the Questionnaire on Eating and Weight Patterns can help identify patients who may need further evaluation

Following any potential approval, health technology appraisal bodies would evaluate the drug's clinical and cost-effectiveness before recommending its use within NHS services: this includes NICE for England, the Scottish Medicines Consortium (SMC) for Scotland, and the All Wales Medicines Strategy Group (AWMSG) for Wales

Histologic evidence from liver biopsiesthe definitive method for diagnosing and staging NASHhas been more limited but encouraging

For overweight or obese patients The weight loss component of these medications opened up a whole new group of potential patients: anyone considered overweight or obese