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How I Approach This With Patients Currently on GLP-1 Medication For patients actively using GLP-1 medications who come to me proactively, before significant skin changes have developed, I focus the conversation on prevention and monitoring rather than correction: supporting skin's structural health through appropriate topical actives, discussing realistic expectations about the pace of weight loss and its relationship to skin's ability to adapt, and establishing a baseline so we can track changes over time rather than only reacting once laxity has become significant

This means that even though the pancreas is still producing insulin, the cells dont respond to it effectively

Sometimes the answer is a higher dose

( 10.1001/jama.2022.0078) [DOI] [PMC free article] [PubMed] [Google Scholar] Darpo B, Sager P, MacConell L, Cirincione B, Mitchell M, Han J, Huang W, Malloy J, Schulteis C, Shen L, et al