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J., Choi, M

In patients with type 2 diabetes, semaglutide also reduces the risk for an adverse cardiovascular event, with decreased rates of MACE (Major Adverse Cardiovascular Events, comprising cardiovascular death, nonfatal myocardial infarction and stroke) [899]

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12,58,59 In a comprehensive systematic review and meta-analysis including more than 34,000 patients with T2DM, semaglutide therapy was not associated with an increased risk of pancreatitis

Collectively, reviews place the proportion of lean mass in total weight loss at ~15% to 40% (or higher in select settings), reflecting differences in drug, dose, baseline composition, and duration