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View at Publisher | View at Google Scholar Arakawa M et al

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Hereby, the mechanisms of the anti-apoptotic actions involve not only protein kinase cascades, but also the modulation of miRNA levels

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While the profile of exendin-4-mediated signalling is more similar to that of GLP-1, there are differences in receptor engagement by the two peptides that can be rationalised by the structural and dynamic data

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Conclusion Our results demonstrate that the appetite-suppressing effects of Ex-4c are mediated through the activation of arcuate POMC neurons

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