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However, the observation that BMD decreased with liraglutide alone but not in combination with exercise, supports the use of exercise with obesity medications in populations with decreased bone mass (eg, after menopause)

[DOI] [PubMed] [Google Scholar] Nakajima T, Nakajima E, Fukiage C, Azuma M, Shearer TR
People who are obese/overweight and vulnerable to health issues

These changes may make it easier to lose fat when combined with proper nutrition, strength training, and adequate sleep, but results vary and weight loss is not guaranteed