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Diabetic and Weight Loss Medication What you need to know about GLP 1 agonists before surgery Whether youre taking GLP 1 agonists as weight loss medication or to manage type 2 diabetes, its important to share this information with your doctorespecially before a scheduled procedure

In obese patients, GLP-1 infusion significantly increased excretion of sodium (by 60%), calcium (by 60%) and chloride (by 44%) and significantly decreased excretion of H + (by 75%)

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Newer compounds like retatrutide add a third receptor target (GIP, GLP-1, and glucagon) and may create unique nutritional challenges that have not yet been well-studied

Fatigue and weakness may occur, particularly during the initial treatment period as the body adjusts to the metabolic effects of the medication