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Peptide: Retatrutide 30mg Type: Longevity Brand: Bio Stem (For research purposes only) Retatrutide is known as a triple agonist, meaning it activates:GLP-1 receptors helps control appetite + slows digestionGIP receptors improves insulin response + nutrient handlingGlucagon receptors increases energy expenditure + fat burning Retatrutide is a multi-receptor agonist currently being studied for its interaction with metabolic pathways, including GLP-1, GIP, and glucagon receptors

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Methods A literature review was conducted using PubMed and Embase to evaluate the impact of severe obesity on morbidity, mortality, and oncologic outcomes in CRC

Timing and severity vary significantly based on dose, individual metabolism, GI sensitivity, and genetic factors affecting GLP-1 receptor function

Efectos metablicos en sujetos con sobrepeso y obesidad