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Phase 3 randomized controlled trials (RCTs) are expected to provide additional insights into the long-term efficacy and safety profile of once-weekly subcutaneous retatrutide

This is a normal and expected response to weight loss, not a side effect of the medication itself

Nutritional imbalances may develop when food intake drops dramatically

Safe weight management should always combine professional guidance, healthy lifestyle habits, and informed decision-making for lasting results

doi: 10.1023/A:1010635131228 185 LiXZhangDVatnerDFGoedekeLHirabaraSMZhangYet al
