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Clinical trials show it affects roughly 1 in 4 users but usually improves within 48 weeks

Read article GLP-1 and Muscle Loss: The 2026 Evidence GLP-1 muscle loss in 2026: see what the STEP and SURMOUNT trials show about lean mass and the two protective strategies that help

Kasyanov E, Pinakhina D, Rakitko A, Vergasova E, Yermakovich D, Rukavishnikov G, et al

These are regulatory and operational standards that exist independently of patient reviews

In June 2025, Emory University, a U.S
