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In the key secondary endpoint for body weight, 12 mg and 36 mg doses led to statistically significant reductions: A1C reduction: 1.2% (3 mg), 1.5% (12 mg), 1.5% (36 mg), 0.4% (placebo) Percent weight reduction: 4.5% (3 mg), 5.8% (12 mg), 7.6% (36 mg), 1.7% (placebo) Weight reduction: 4.2 kg (9.3 lbs

Thus, the underlying effects of prediabetes (or diabetes) may alter or interfere with the intended optimal use and benefit of this medication

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