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Published in 2025, it was the first trial to directly compare tirzepatide (the active ingredient in both Mounjaro and Zepbound) against semaglutide (the active ingredient in Wegovy) in adults with obesity but without type 2 diabetes

To further evaluate random donor DNA integration, we performed 5RACE analysis to identify upstream sequences of scExe4 mRNA transcribed from integrated donor DNA in liver samples from knock-in mice (Supplementary Fig

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95% CI, 0.29-0.96) and meningioma (HR = 0.69