celebrities on semaglutide Everyone’s Talking About It — So Let’s Talk About It Too!, Ozempic and other GLP-1 medications like and Tirzepatide have taken over headlines, TikTok, and Hollywood. are raving Hollywood doctors investigate which Met

More insights on managing these concerns are available

It seems as if this new class of metabolic treatments is something quite unlike anything we have had before in medicine, with applications across many of our most chronic diseases

modification Obesity and IBD by @EdwardLoftus2 Obesity is a chronic inflammatory state Adipose tissue is not biologically inert (TNFa, IL-6, IL-8, leptin, adiponectin) Postulated role in the pathogenesis of IBD Potential risk factor for adverse outcomes Trends in BMI among IBD patients at diagnosis in Olmsted County Doubling of obesity rates in 20 years in CD and UC (Johnson AM JCC 2021 and J Clin Gastro 2024) Obese patients more likely to have a colonic phenotype

Retatrutide requires ongoing weekly administration, making total cost over time more relevant than single purchase price

Curr Diabetes Rev 14(3):273279 Mousavi A et al (2025) Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials