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Even though the exact mechanism of action is not known, phlebotonics are thought to increase venous and lymphatic drainage, normalize capillary permeability, and decrease inflammation in the hemorrhoidal cushions

The coverslips were mounted using the Duolink in Situ Mounting Medium followed by imaging the cells with BioTek LionHeart fluorescence microscope

To bridge this gap, future research should prioritize studies designed to address the generalizability of TTE analyses in real-world settings
