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The study is organized by Scripps Research and aims to enroll 1000 participants.
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An active-comparator new user study design was used to minimise risks of confounding and time related biases from using real world studies of drug effects
The mouse models included lean mice (C57BL/6J and NSY.B6- a / a ), obese diabetic mice (NSY.B6- Ay / a ), proglucagon-deficient mice ( Gcg -/-), glucose-dependent insulinotropic polypeptide (GIP) receptor-deficient mice ( Gipr -/-), and ATP-sensitive potassium channel (KATP channel)-deficient mice ( Kcnj11 -/-)
