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We examined the effects of d-allulose on feeding behavior including arrhythmic hyperphagia that is characteristically associated with obesity and diabetes 3,4 and on glucose metabolism by glucose tolerance test (GTT), insulin tolerance test (ITT), and pyruvate tolerance test (PTT), and explored underlying mechanisms involving GLP-1 release and vagal afferents using Glp1r knockout mice ( Glp1r KO), surgical vagotomy and Glp1r knockdown specifically in vagal afferents using viral-mediated shRNA

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It suggests these drugs dont just blunt craving

Why is this happening now

In this blog post, we will delve into the mechanisms of action of retatrutide, explore its impact on various metabolic parameters, and discuss its potential as a valuable tool for enhancing metabolic health