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Notably, beyond the canonical mesolimbic reward system, recent work has identified a critical role for GLP-1 signaling in the MHb and IPN

Thats due to the nature of tirzepatides molecule, says Kathryn Horton, MD , a board-certified internal medicine physician and expert contributor at Drugwatch.com

Our medical team and board members help oversee each of our treatments to ensure our medical assessments are thorough, safe, personalized, and provide best-in-class care

PMID: 38804080 Br J Pharmacol Exendin-4, a GLP-1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia-reperfusion injury

3,249 patients were excluded due to missing demographics, age 40 years, missing demographics, prior use of any study drug, diagnosis of type 1 DM, retinal disorders classified based on the ICD categories (DR, retinal vascular occlusion, separation of retinal layers [including all types of retinal detachment and central serous retinopathy], degeneration of retina, chorioretinal inflammations, and other retinal disorders [including retinal hemorrhage, vitreous hemorrhage, retinal edema, etc.]), history of receiving vitreoretinal interventions (intravitreal injection, laser coagulation, and vitrectomy), no baseline glycosylated hemoglobin (HbA1c), or no follow-up data in the subsequent 6 months after being prescribed the medication, were excluded from this study