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Retatrutides triple-receptor design is part of this evolution

They may write a prescription for a specific medication or recommend over-the-counter substitutes

As with other medicines in the incretin-based therapy class, retatrutide's clinical trials have identified a range of side effects, most of which relate to its gastrointestinal activity
[DOI] [PubMed] [Google Scholar] [123].Buse JB, Nauck M, Forst T, Sheu WH, Shenouda SK, Heilmann CR, Hoogwerf BJ, Gao A, Boardman MK, Fineman M, Porter L, Schernthaner G, Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomised, open-label study, Lancet, 381 (2013) 117124

This marks a significant breakthrough for patients who want the benefits of GLP-1 medications without the need for weekly injections
