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5: Wang D, Wang J, Li B, Yang S, Guo F, Zheng B, Wang J

A separate research letter published in JAMA identified an average percentage of days covered (PDC) of 54% in patients with obesity and without diabetes 12 months after GLP-1 RA initiation

Body composition: Monthly if using a bioimpedance scale (understanding its limitations), or quarterly via DEXA scan for the most accurate fat and lean mass measurement

Other potential risk factors Several other potential risk-modifying factors were explored but were removed from adjusted analyses due to not being independently significant as covariates and not contributing significantly to the information criterion

Traditional treatments primarily focused on suppressing appetite or inhibiting fat absorption