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Additionally, some patients experience changes in gastric acid secretion, which further impacts how efficiently food is broken down

Consult your GP if you are still unsure whether you will take your medication early, late, or skip your dose, so they can give you personalised advice

For most patients with CKD, the approach is to start with an SGLT2 inhibitor as the kidney-protective foundation, then consider adding a GLP-1 if the patient also has obesity, needs additional blood sugar control, or has elevated cardiovascular risk

Fatourechi V

Card Fail Rev 10:e05 Pitt B, Pfeffer MA, Assmann SF, Boineau R, Anand IS, Claggett B et al (2014) Spironolactone for heart failure with preserved ejection fraction