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"If taking medications that decrease appetite or insulin requirements, people with type 1 diabetes still must continue taking their long-acting insulin or using their insulin pump." Semaglutide, vomiting, and DKA: A case study In a 2023 case report, a person with type 1 arrived at an emergency room with ketoacidosis, after suffering nausea and vomiting attributed to taking Wegovy (semaglutide) prescribed by his endocrinologist for weight loss
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In particular, the discovery of GLP-1 receptors in cardiovascular tissues opened new therapeutic possibilities beyond glycemic control

And some evidence suggests the drugs may protect the brain, too

A safer approach is to use psyllium before meals
