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Whilst these medications offer significant therapeutic benefits through appetite suppression and improved glycaemic control, the resulting reduction in food intake may affect nutritional status in some individuals

Marketing language is another area to watch

Post-meal pharmacodynamic profile of lixisenatide once daily vs placebo in T2DM insufficiently controlled on SU metformin (GetGoal-S) (Abstract D-0743)

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Additionally, motor dysfunction in PD patients leads to reduced physical activity, further affecting energy consumption and metabolism ( 3.1 PD and insulin resistance Insulin resistance (IR) is usually considered a systemic response or reduced sensitivity to insulin effects