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The commonly prescribed GLP-1 drugs include semaglutide and liraglutide

Compounded GLP-1 Peptides (semaglutide and tirzepatide) are a physician prescribed medication that contains the same active pharmaceutical ingredient(s) as the name brand FDA-approved medication like Ozempic, Wegovy and Monjauro.

This review outlines the impact of metformin on the digestive system and explores potential explanations for variations in metformin effectiveness and adverse effects like gastrointestinal discomfort

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Budak , et al

When to seek medical advice : Patients should contact their GP or diabetes specialist nurse if they experience: Severe, persistent vomiting preventing adequate fluid intake (risk of dehydration and acute kidney injury) Severe abdominal pain, particularly if radiating to the back (potential pancreatitisrare but serious) Right upper abdominal pain, fever, or yellowing of skin/eyes (potential gallbladder disease) Sudden vision changes (particularly with semaglutide, which may worsen diabetic retinopathy, especially with rapid HbA1c reduction) [40] [41] Signs of hypoglycaemia when used with insulin or sulphonylureas Allergic reactions (rash, difficulty breathing, facial swelling)call 999 or go to A&E for severe allergic reactions Patients should report suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)