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nausea decreases with ongoing usage a steady weight loss occurs in some patients over 2 years (may be related to nausea & CNS-mediated loss of appetite) there is an increased risk of hypoglycemia when exenatide is used with a sulfonylurea The dose of the sulfonylurea may need to be reduced if hypoglycemia occurs when combined with exenatide Most serious : rare & sometimes fatal necrotizing or hemorrhagic pancreatitis When initiating patients on Byetta, watch for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back, which may or may not be accompanied by vomiting)
Your healthcare team can also review whether your current GLP-1 dose remains appropriate or whether adjustment might improve tolerability whilst maintaining therapeutic benefit
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Taking the time to understand this process elevates the quality of your work and brings you one step closer to discovery
Their anti-inflammatory and insulin sensitization properties in the brain may help explain the antidepressant effects seen in some patients
