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Specifically, patients were matched on age, sex, race, ethnicity, hypertension, insulin use, atherosclerotic coronary disease, hypercholesterolemia, disorders of lipoprotein metabolism, neoplasms, ischemic heart disease, chronic kidney disease, nicotine dependence, surgery, hospital inpatient and observation care services, BMI, hemoglobin A1c, and total cholesterol

Crucially, this research identified distinct biological signatures in the patient cohort, including significantly reduced levels of butyrate and elevated markers of systemic inflammation

It is a biologically driven disease

Some people experience weight regain if previous eating patterns resume, while others maintain weight loss through continued healthy habits

Killian, D