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Average weight loss is 15-20% of body weight in 12 months

Mounjaro and Zepbound show even more promising outcomes, with weight loss reaching up to 21% at higher doses

These medications mimic the action of a natural hormone called Glucagon-Like Peptide-1 (GLP-1), which plays a vital role in regulating appetite and blood sugar

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Mice were then divided into four weight-matched and liver function-matched groups (n=7 per group): NC group (C57BL/6 mice), Vehicle group (ob/ob mice), 50 mg/kg cinchonine group (ob/ob mice), and 100 mg/kg cinchonine group (ob/ob mice)