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It remains an investigational medicinal product (IMP), meaning it is only available within the context of authorised clinical trials

Annu Rev Physiol2008;70:239-55

Prescribing rates (reported per 1,000 women) were defined as the number of women with a progesterone-containing HRT prescription divided by all women aged 45 years and older with prescription data during a given month

Higher doses do not introduce unexpected or entirely new side effects

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