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Restoring Ovulation through Weight Loss In limited studies, GLP-1s are associated with a more regulated menstrual cycle

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Pharmacology Insights Some interesting pharmacological features: * Oral bioavailability: ~98% * Half-life: ~26 hours * Mainly metabolized via CYP3A4 * Once-daily dosing possible due to prolonged action Why Baxdrostat Matters Baxdrostat represents a shift toward targeted hormonal therapy in hypertension

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21 The most significant headwind will be felt by companies with a portfolio centered around food high in salt, sugar and fat, or alcohol