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49: Gastric Secretion (Elsevier, 2010)

Phentermine works by influencing the central nervous system to decrease appetite, but it does not directly burn fat or boost metabolism

To maintain the results of a weight loss medication, you should expect to continue taking it long-term
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Bupropion/naltrexone has been shown to lead to 5% weight loss after 12 weeks of treatment, with sustained weight loss over 56 weeks 1

Given the lack of individual preclinical models of PCOS that recapitulate all the metabolic, endocrine, and gonadal traits of the clinical syndrome, pharmacological testing was conducted in parallel in these two PCOS models, which are among the most reliable to mimic the metabolic and gonadal phenotype of women with PCOS 36,37 , capturing also the heterogeneity of this condition 38