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More serious complications, such as gastroparesis and bowel obstruction, though less frequent, have been reported and warrant close monitoring, particularly in vulnerable populations [81]

This discomfort typically results from the medication's formulation pH, tissue distension, or individual sensitivity

For example, CYP3A4 represents a CYP enzyme belonging to family 3 [15], subfamily A, and protein 4 in subfamily A

The table below summarizes typical incidence and expected duration for quick reference
