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2025;2:101430 DOI: Received: January 17, 2025 Accepted: April 03, 2025 Published: April 28, 2025 Academic Editor: Tzong-Shyuan Lee, National Taiwan University, Taiwan, China The article belongs to the special issue Metabolic Syndrome in Menopause Hormone replacement therapy (HRT) is essential for alleviating menopausal symptoms and mitigating complications linked to type 2 diabetes mellitus (T2DM) in postmenopausal women