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Common gastrointestinal side effects include: Nausea and vomiting : Usually most pronounced during initial treatment and dose escalation, often improving over 48 weeks Diarrhoea or constipation : Can affect hydration and nutritional status Abdominal discomfort : Typically mild and transient Patients can manage mild gastrointestinal symptoms by eating smaller, more frequent meals, avoiding high-fat foods, staying well-hydrated, and taking the medication as directed

It can identify solid gastric contents or increased gastric volume and may guide decisions about proceeding, delaying, or modifying the anesthesia plan

Why it matters The findings carry weight given the medications reach

Early Treatment Diabetic Retinopathy Study Research Group

Taranto-Montemurro L, Sands SA, Edwards BA, et al