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Description
They enhance glucose-dependent insulin secretion, suppress glucagon release, and slow gastric emptying, while supporting the preservation of pancreatic beta-cell function

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The most prevalent side effect of Exenatide is nausea, which may explain its weight loss effects [227]

Adults on GLP-1 receptor agonists for extended periods show reduced risk of cognitive decline and dementia in several observational and trial datasets, with effect sizes ranging from modest single-digit reductions to much larger ones, depending on the cohort

While laboratory findings and observational studies suggest potential benefits against the biological drivers of dementia, results from large clinical trials in people with established Alzheimers are still inconclusive
