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GLP-1 Receptor Agonists and Aspiration Risk: From Universal Holding to Risk-Based Perioperative Management Review Abstract Purpose The rapid adoption ofglucagon-like peptide-1 receptor agonists (GLP-1 RAs)anddual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 (GIP/GLP-1) receptor agonistshas transformed the management of type 2 diabetes mellitus and obesity

Inphase 3 clinical trials (SURPASS 1-5), the dose-dependent efficacy and safety of tirzepatide were assessed by once-weekly subcutaneous injection (5mg, 10mg, and 15 mg), as monotherapy or combination therapy, in individuals with T2DM

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