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Furthermore, it is possible that somatostatin directly inhibits glucagon secretion by binding to its receptor in the alpha cell, since GLP- 1 stimulates islet somatostatin secretion directly through the canonical GLP- 1 receptor, expressed on delta cells [71]

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August 15, 2025: Trulicity May Not Protect Patients Hearts As Much As Its Competitor Does Trulicity competitor (Mounjaro) may be 8% more effective at preventing major adverse heart events than Trulicity