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In participants without diabetes, treatment with the 7.2 mg dose resulted in an average weight loss of nearly 19%, outperforming the 16% reduction seen with 2.4 mg and the 4% seen with placebo

These findings offer the evidence base to support the use of semaglutide 2.4 mg weekly in patients with a history of MBS and the rationale for suboptimal clinical response, posing an indication for treatment

In a skeletonized face, facial fat (which forms the faces cushioning) atrophies and bony ridges are accentuated

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