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If you experience any suspected side effects from either medication, you can report them via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

In retatrutide trials specifically, starting at 4 mg instead of 2 mg nearly doubled early GI symptom rates

The mechanism behind this heart rate increase is not fully established but may involve changes in autonomic nervous system activity or other physiological adaptations

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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.The role of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in diabetes-related neurodegenerative diseases
