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Description

Study Selection The trials we included met the following criteria: (1) RCTs that compared GLP-1 receptor agonist with a placebo or active control (other antidiabetic drugs or insulin), (2) patients with type 2 diabetes, type 1 diabetes, prediabetes, overweight or obesity, (3) with durations of at least 24 weeks, and (4) reported the occurrence of at least one case of various thyroid disorders as adverse events

Recently, anecdotal accounts and raw event incidence reports prompted FDA to review a potential association between GLP-1 RAs and suicidal ideation

Clinical Evidence : Clinical trials have shown Semaglutide to significantly reduce HbA1c levels and promote weight loss in adults, supporting its use in diabetes and weight management

PlexusDx's Precision Peptide Genetic Test ($99 after your first month) analyzes your GLP1R genetic variants to predict how strongly your body responds to semaglutide therapy