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In addition, due to the lack of sufficient clinical data, larger samples and longer-term clinical studies are needed to confirm the effects of enterokinetic hormones on bone metabolism and to explore the exact mechanisms involved

The weight loss from these medications is substantial

The question nobody wants to ask: Will I regain weight if I stop? Many people do regain some weight if they discontinue, because obesity is a chronic metabolic condition, and the appetite/biological drivers can return

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Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus