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SGLT2 inhibitors were chosen as the comparator given they are guideline-recommended second-line glucose-lowering medication and share similar cardiovascular benefits with GLP-1RA, which helps reduce confounding by indication

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10.1111/bph.16421 9 ChengY.LiuP.XiangQ.LiangJ.ChenH.ZhangH.et al (2022)

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