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Scientific results have been mixed when comparing liraglutides effectiveness on weight loss against semaglutide and tirzepatide

However, despite its small size (39 amino acids) and low effective dose, Exe4 has a short half-life, requiring frequent injections similar to other biologics

Even if the impact would be bigger than that, I think over a 10-year period, it will be manageable, and we will have adequate lead time to adjust and prepare for any changes that we see. On a more practical note, he said, Obesity rates around the world are very different, and we have one of the lowest exposures since 75% of our sales come from outside of the US and 40% of our sales are in emerging markets [where average BMIs are far lower]

However, limited availability and high costs have made it challenging for many patients to begin or maintain therapy

PubMed CrossRef Lorenzi M, Ploug UJ, Langer J, et al