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Their common sequence, exendin 2029, specifically inhibited CAP-induced TRPV1 activation without affecting proton-induced activation and similarly alleviated CAP-induced nociceptive behaviors

Within the hypothalamus, GLP-1 interacts with pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (it seems to have limited direct access here), a classic site involved in appetite regulation and energy expenditure

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Effect of Exercise on Ovulation: A Systematic Review

This distinction has direct implications for in vitro receptor research native GLP-1 provides a physiologically authentic agonist reference for local/paracrine GLP-1R signalling studies, distinct from the systemic receptor engagement profile of long-acting GLP-1RA analogues