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In addition to nausea and vomiting, the most common adverse reactions of exenatide long-acting preparations also have a strong immunogenic reaction at the injection site, which is mainly caused by the rejection of polylactic acid-glycolic acid copolymer

Spironolactone: Anti-androgen sometimes prescribed off-label for female hair loss, particularly when androgenetic alopecia is unmasked

Patients achieved substantial weight loss during the initial GLP-1 RA phase (~1822% at 12 months), which was subsequently maintained after its discontinuation, with total weight reduction reaching 25.5% (95% CI 23.127.9%) at 593 days, with most patients on metformin

Another study found that participants regained an average of 11.6% of their body weight within a year after stopping treatment

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